Graduate student reagents-researchers invent new instruments to test brain damage without entering the brain

According to a report by the Spanish newspaper Le Monde on February 10, at first glance, this instrument consists of two simple yellow hoses that children can press with their hands or touch unconsciously. One hose receives manual stimulation and the other is a fake receiver. Both hoses are connected to a computer, and this computer is also responsible for receiving brain waves from sensors placed on the child's head. These sensor tubes are called biological neural-like (ERP) according to their function. This seemingly complex instrument is actually used to monitor brain activity. The advantage is that it can easily and safely obtain brain activity information without using the method of entering the brain, so it is especially suitable for brain development examination of premature infants. However, in the past, it would take at least three years to check the baby's brain development for pathological changes.

Vanderbilt University researchers publicly display videos of their research and development results. Through the video, you can see that the child receiving this tester needs to fix a finger on the plastic touch tube and keep the head from moving. The tube on the finger and the dense sensors on the head will transmit information to a computer. The computer will test the plasticity of the neuron, in other words, it can detect whether the brain will develop in the future. In addition, the children in the video did not feel any pain or any resistance, which means that this instrument will not cause any damage to the children. The research invention has been published in the American Journal "Visualization Experiment".

Of course, the necessary condition is that the children under test should be at least infants and young children with certain cognitive consciousness. In the case of accepting the test, it is important to choose different test methods according to different children. Need to find something interesting for children to attract children's attention to achieve nerve stimulation. For example, some parents will show cartoon pictures on the iPad screen to achieve the effect of hypnotizing children. This is also part of the test, which can simultaneously stimulate children's hearing and touch. To test children's hearing more effectively alone, the researchers will make the speaker placed above the children's head sound. In order to allow some babies to take the test comfortably and quietly, their parents or caregivers can hold them during the test.

The purpose of the development of this instrument is to hope to get children's response to visual and auditory stimuli through touch, which is the so-called somatosensory experience. To do this, the electrode grid is placed on the head of the baby or child and the sensor under the index finger is fixed with a velcro. Through these two sensors, the computer can obtain the stress results of the children.

During the experiment, children need to press the plastic touch tube at least 120 times because they will be asked to focus on one task. For example, older children need to count air bubbles by pressing a plastic touch tube, but if they are younger babies, they will not be asked to do this task because they are too young to concentrate.

This research method is a proof-of-concept (not just to prove technological progress). This study is helpful to distinguish between young healthy infants and infants with intellectual disabilities, because the difference in intellectual development is not visible from the appearance of the infant. The inventors admit that "it is indeed impossible to distinguish babies with abnormal intellectual development", but they believe that those brain neuropathies will be reflected in the baby's brain waves, and healthy baby brain activity is more active. In addition, the tester has improved the hand touch receiver tube in the development of the new version compared to the old version system, so that even if the children under test cannot actively participate in the test task, it will not affect the accuracy of the test results.

Although the study still lacks a large number of experiments, the researchers believe that the device can be used in more cases, including testing infant brain injury. "This test can also predict limb motor function," the R & D staff added that it will further improve the field of application of the test instrument.

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