The world's first "personal version" gene map completed

All human DNA sequencing maps were announced in 2003. At the time, it was the 50th anniversary of Watson and Crick's discovery of the DNA double helix. This project cost a total of 400 million US dollars.

The sequencing work of the world's first "personal version" of the genome map took only two months and cost $ 1 million.

The newspaper ’s comprehensive report, the American Nobel Prize winner James Watson, known as the “father of DNA”, received a special gift on May 31: a DVD disc containing his own complete genome map, which is also the world ’s The first "Personal Edition" genomic map deciphered on the Internet. Watson said that for the purpose of scientific research, he plans to make his "personal version" gene map public.

Decoding "Personal Edition" takes only 2 months

In 1962, the 79-year-old James Watson won the Nobel Prize in Physiology and Medicine with his colleague Francis Crick. For more than 50 years, Watson has been devoted to the study of the double helix structure of DNA (deoxyribonucleic acid) molecules. Regarding the gift of the "personal version" of the genome map, Watson said: "I am very excited to see my genome map." This genome map disc was created by the Human Genome Sequencing Center of the Baylor College of Medicine and "454 Life Sciences" "Company" was completed in cooperation.

Richard Gibbs, director of the Human Genome Sequencing Center, said: "There is nothing more meaningful than congratulating Watson on the completion of the personal genetic map." Watson jokingly said that he was responsible for this When the project was completed, he was alive and surprised.

Not long ago, Watson donated his genetic samples to the Human Genome Sequencing Center of Baylor College of Medicine and "454 Life Sciences" to allow researchers to sort out the personal genome map. This work took only 2 months and cost $ 1 million.

The completion of the "personal version" genomic map indicates that any individual's genomic map can be quickly sequenced in the near future, and the cost will continue to decrease, which is expected to soon fall below $ 1 million. With the advancement of technology, the continuous reduction of the time and cost required to produce the "personal version" of the genomic map is heralding the coming of the era of personalized genomic medicine.

Celebrities have followed suit

Watson's special prize is unprecedented, and it has attracted a large number of celebrities to follow suit. According to reports, people who are queuing to sequence individual genes include physicist Stephen Hawking, famous American TV host Larry King, and Paul Allen, one of the founders of Microsoft.

According to the plan, the genome of each celebrity will be sorted, made into a compact disc, and published on the Internet. Their genetic maps, the factors that determine a series of characteristics such as their height, eye color, and susceptibility to diseases, will be made public. In addition, Watson also privately recommended British celebrities such as football star Rooney and supermodel Kate Moss as candidates for the genome disc.

The decipherment of the genome map is a "book of life" containing personal information. Whether its private information is made public and whether the disclosure of personal genetic information should be restricted is currently at the stage of controversy.

Watson said he understands the fear of being discriminated based on genetic factors, but this concern is exaggerated. Researchers who completed Watson's "Personal Edition" gene map said that Watson's genome contains many variant chromosomes, some of which are directly related to cancer. It is reported that Watson has suffered from skin cancer since he was in his 20s. Watson said he allowed his genomic information to be put on the Internet for scientific research, also to prove to the society that such information is not terrible.

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