The four-sided sealed pouch form has been widely used by pharmaceutical companies in the production of various product dosage forms, such as granules, powders, and oral liquids. With the increasingly widespread application of pouch packaging, pouch packaging technology has also been widely concerned by users. In this issue of the Pharmaceutical Packaging Technology section, we invited the German Medicis Co., Ltd. to discuss the topic of medical sachet packaging with users of three pharmaceutical companies. We hope this column will inspire readers to maximize the energy of the pouch packaging equipment. .
Guangzhou Pharmaceutical Group Guangzhou Xingqun Pharmaceutical Co., Ltd. Chief of Equipment: Zhang Jun
The key indicators of Medisi equipment can meet our many strict requirements
In February 2002, Guangzhou Xingqun Pharmaceutical Co., Ltd. entrusted the import equipment procurement department of the Guangzhou tendering center to tender for the pouch pharmaceutical packaging equipment. At that time, a total of four foreign manufacturers, including German Medici Co., Ltd., participated in the equipment bidding process.
Guangzhou Xingqun Pharmaceutical Co., Ltd. has conducted rigorous overall evaluation, comparison and trial operation of the technology and products of several bidders. Compared with the drum heat sealing method applied by other three suppliers, the German Mexixi bag packaging equipment applies a flat pressure heat sealing method, which can guarantee the sealing quality of the pouch product under the condition of guaranteeing the measurement requirements. In addition, the customer also found that Medsy's products have relative advantages in terms of the smoothness of equipment operation, the convenience and habitability of maintenance operations, the feeding system, the quantitative system, the control of packaging tension, the control of material centering, and the pressure control of embossing. The obvious advantages and features of other manufacturers. Under the unanimous approval of relevant experts from the Guangzhou tendering center, Xingqun Pharmaceutical Co., Ltd. finally chose to cooperate with Germany's Medici. Two sets of LA500 pouch packaging machines and one LA500+P700 pouch packaging and loading line were introduced.
Stellar Pharmaceutical customers said that pharmaceutical companies will first consider the quality of equipment maintenance of pharmaceutical products, and relevant key indicators of Medisight equipment to meet the strict requirements of customers on the production process, such as differences in the amount of equipment, production speed, equipment suitability ( Including the applicability of equipment to packaging materials and granules, heat sealing performance and appearance quality, auxiliary accessories, etc.
Mr. Zhang summarized several major advantages of Medisix's equipment:
a. The difference in the minimum loading capacity of Medisi equipment can be controlled within 1%.
b. The bags used to package the granules are packaged in pure aluminum foil and aluminized composite membranes. Medisix's equipment is very compatible with the two types of packaging materials, production is very stable, and at the same time it also shows good adaptability to the granules of the drug itself.
c. The heat-sealing process of Medsy's equipment is controlled by hydraulic pressure, and the performance is stable. The bag sealing performance of the manufactured bag is good.
d. Easy to clean, good production stability.
Medicis has a saying: I hope to further automate the volume control
Due to the different adhesion caused by different manufacturing process control, the particle density of the granular product is different, and the slight density change response in the high-speed automatic production operation brings the need for adjustment. At present, Medisix equipment fills six bags of products (six channels) for one working session, and six metering systems perform separate, manual filling and volume control. It is hoped that Medisis can automate the volume control and measure the change of the quantity in time through the high-speed measuring balance after conveying the product on the conveyor belt. According to the real-time different product particle density to adjust the amount of loading, and directly through the servo motor to automatically control and adjust the capacity.
Medici can provide independent servo control of the measurement system for each channel. The measurement of the product is more flexible and convenient than the metering system currently used by the user. The switching time of the replacement product measurement specification can be accomplished by selecting the menu of the machine control panel, which is especially suitable for products that require frequent replacement of product specifications and products whose batch volume cannot be controlled stably.
Jiangxi Huiren Pharmaceutical Group workshop director: Xuejun Xue
Small difference in loading capacity, 5 LA-500 runs well
In 2000, Jiangxi Huiren Pharmaceutical Group introduced 5 types of LA-500 high-speed granule pouch packaging machines from Germany's Medicilon through an open bidding process. Based on the main characteristics of its own products (3.6mm~3.7mm pellets, powders, granules, etc.), a small-scale trial was conducted, and different loading barrels, measuring cups, and contents were used as the inspection methods to evaluate the equipment's installation. Quantity differences and other indicators. Mr. Huang said that the difference in LA-500's capacity is very suitable for the needs of the company. In addition, Mr. Huang also said that the outstanding performance of this device in other areas is also an important reason favored by companies:
Previously, the customer Jiangxi Huiren Pharmaceutical Group was using a domestically-made single-channel pouch packaging machine. There were 30 production units in the plant area, and the equipment was laborious and the production area was large. After the introduction of Medicilon equipment, the production of Huiren Pharmaceutical products was in good condition, and the number of production operations and operation and maintenance costs were greatly reduced. The application of PLC technology makes the device easier to operate.
b.Medici equipment adds stirring and oscillating devices at the material feeding section, and at the same time it shows a small amount of difference in the filling of pills, powders, granules and other products.
c. Excellent safety performance. Careful attention is paid to the design of the installation control and the configuration of protective measures, and the automatic protection of the machine stops when the operation is not standardized.
Medicis has something to say: Look forward to further increase the flexibility of the equipment on the packaging size specifications
The flat pressure design of the Medici equipment determines the length and width of the pouch. The width specification is related to the location of the vertical seal of the heat seal station, and the length can be adjusted by setting the parameters. Therefore, it is hoped that Medisix's equipment will perform better in the adjustment of package specifications.
The length specification of the pouch can be adjusted within the operating parameters of the pouch machine without the need to change the size part. The change of the width specification of the pouches can be achieved simply by replacing the positioning plate at the width of the die, without replacing the entire set of die, and the die positioning plate is of low value. Other workstations, such as measuring, slitting, and pulling, can be adjusted in width and position.
Shijiazhuang Shenwei Pharmaceutical Co., Ltd. Engineer: Bai Fujun
Good sealing and production line synchronization
In 2001, Shijiazhuang Shenwei Pharmaceutical Co., Ltd., through a comprehensive evaluation of equipment procurement tenders, chose to cooperate with the German company Medici in three well-known foreign suppliers. At the end of 2001, Shenwei Pharmaceutical purchased two sets of LA500 pouch packaging equipment and a P700 type cartoning machine for MDS and later purchased a P700 cartoning device. At present, the two-bag packaging and cartoning line works well at the customer's factory.
a. Unique heat sealing method:
The earliest packaging used by customers was a three-side sealed pouch, and the four-side sealed pouch package had a more upscale appearance, which was significantly better than the three-side seal. Compared with the continuous drum type working methods commonly used in domestic equipment, Medisix products use intermittent flat heat sealing methods with technical advantages. The bags and packaging products produced are obviously superior to domestically-made traditional equipment in terms of appearance and flatness.
b. Good transmission coordination
Compared with the domestic traditional equipment, the Mdixie pouch packaging machine has very excellent performance in matching with the cartoning equipment during the high-speed operation, and the equipment is very stable and synchronous.
Medicis has something to say: look forward to equipment can further improve the speed of operation
At present, our company's introduction of the Medisix pouch packaging machine using domestic packaging materials can achieve a production speed of 560 bags/minute (8 channels, 70 cycles per minute). If we can further improve the speed of the machine, we believe that it will bring greater economic benefits to users.
The high-speed operation of the machine is not only the desire of the user, but also one of the main features of the equipment that Medicsi pursues. Medicilon will continue to work hard to optimize and improve the performance of the equipment, provide users with updated technology and equipment performance, and develop together with the majority of pharmaceutical companies.